Alisa, 13, and her mother Baiba Sniedzina, 52, were last seen in Devonshire Avenue, Portsmouth, just before 3.30pm today (17 March).
Baiba is not currently the legal guardian of her daughter and has taken her without permission.
Officers are currently following several lines of enquiry to locate them and are appealing for anyone who may have seen them to contact them immediately.
Alisa is described as being 5ft 4ins tall and of slim build. In the picture above, you can see she has mousy brown hair with blonde tips.
She was wearing a mustard-coloured top and black leggings. She was also carrying a teal coloured hoodie.
Baiba is described as being 5ft 10ins tall. In the picture above, you can see she has short blonde hair. She was wearing a black t-shirt and leggings.
If you have seen Alisa or Baiba, or know where they are, please call us on 999, quoting 44220106864.
Alternatively, you can call Crimestoppers anonymously on 0800 555 111.
Please can we ask everyone to carefully consider any responses to this post and that you do not speculate about any circumstances?