Officers from the Met Police have cordoned off Lordship Lane in South East London following a fight that has left a woman fighting for his life.
Police and paramedics were called on Friday evening after a woman was seriously injured following the fight that took place at around 10.45pm.
The Road is closed in both directions at the junction with Barry Road due to an incident being attended by the London Ambulance Service.
Local buses route and night buses that service the area have also been affected by the closure these being 12, 40, 176, 185, 197.
Officers attended along with London Ambulance Service. A 36-year-old woman was found with stab injuries and taken to hospital where she remains in a life-threatening condition.
A man was subsequently arrested on suspicion of attempted murder. He has been taken into custody at a south London police station.