Nasim Khan, aged 23, of Radnor End, Aylesbury, and Mohammed Humzah Wasim, aged 19, of Thrasher Road, Aylesbury, were each charged with one count of murder.
The charges are in connection with an incident in Lembrook Walk, Aylesbury in which a man aged in his twenties sadly died following reports of a large fight.
Another man was injured in the incident, but has since been discharged from hospital.
Four other men, all from Buckinghamshire, have been released on conditional police bail, while three other men, also from Buckinghamshire, remain in custody at this time.
Khan and Wasim will appear at High Wycombe Magistrates’ Court on Monday.