The fire was started deliberately at the door of a house in in Milgate Street, Royston, where Lindsey was staying at around 4.30am on 8 September 2001.
Firefighters rushed to the property, doing everything they could to rescue her from the flames.
They carried Lindsey from the first floor of the house, but she sadly died two days later due to smoke inhalation.
An investigation was launched and officers worked with partners in the fire service to investigate the cause of the blaze.
Despite long-running enquiries made by police, the suspect has never been identified or prosecuted.
Dave Stopford, head of the Major Incident Review Team said: “Two decades have passed since Lindsey’s death, but the pain of her loss is still felt by many who loved and miss her.
“There may be someone out there who knows a crucial detail about the events leading up to the fire. I would urge anyone with information, even if it may have seemed insignificant at the time, to come forward.”
If you have any information about this incident, that has not already been passed to South Yorkshire Police, please contact the Major Incident Review Team, on 0114 296 1399, quoting reference: 14SY020106B01. Any information will be treated in confidence.
Alternatively, if you would like to remain completely anonymous, or do not feel comfortable speaking to police, you can call the independent charity Crimestoppers. Their telephone number is 0800 555111 or you can submit information via their website crimestoppers-uk.org.